With aging population, the rise of obesity or growing interest in sport, the frequence of degenerative cartilage pathologies is increasing.
Except for Osteochondritis, cartilage pathologies always begin with the superficial surface layer and then extend to the depths in the cartilage matrix.
There are several cartilage gradation systems such as ICRS (International Cartilage Repair Society) or WORMS system in MRI (both available in Vitrea) (Figure 1.).
Knee Osteoarthritis (OA) is a chronic joint disease, characterized by progressive destruction of joint cartilage, leading to pain and loss of function. This pathology affects more than 39 million people in Europe and this figure will probably double by 2020 (Figure 2.).
There are three stages of Osteoarthritis:
- early stage: joint cartilage degeneration occurs,
- intermediate stage: onset of the first radiological signs,
- advanced stage: full-thickness loss of cartilage and joint cartilage has disappeared.
Degenerative osteoarthritis is a chronic mechanical disease that differs from inflammatory osteoarthritis, which is an acute inflammatory disease.
Diagnosis and treatments are different.
Plate let-rich plasma (PRP) is a blood derivative product.
The PRP is collected from blood and isolated by centrifugation. There is no risk of “rejection” or allergy since blood is drawn from the patient (autologous). Patient’s own platelet that has growth and healing factors are used.