Differential Tissue Harmonic Imaging (D-THI)

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Previous technology reduced imaging artifacts by detecting the second harmonics generated by nonlinear effects. However, since the second harmonics are high-frequency signals limited to a narrow frequency band, the sensitivity and image resolution are low, resulting in body surface examinations.

To overcome this problem, Canon developed Differential Tissue Harmonic Imaging (D-THI) which simultaneously transmits two types of ultrasound waves with different frequencies and creates a composite wave of the second harmonic and the differential harmonic (as well as the second harmonic) generated by the nonlinear effects in the received waveforms. This composite waveform consists solely of the reflected wave components due to nonlinear effects and achieves a wide bandwidth from low to high frequencies.

As a result, high-resolution images with good sensitivity can be acquired in both superficial and deep regions while retaining the advantages of conventional diagnostic ultrasound technology, such as fewer image artifacts.

Technology and clinical value

D-THI has expanded the use of ultrasound by providing details in areas that were previously difficult to see such as structures in deeper regions, bowel, and MSK, supporting clinicians to begin treatment as quickly as possible.

Watch our interview video where Tetsuya Kawagishi who is the father of D-THI and Prof. Thomas Fischer from the Department of Radiology, Charité University Medicine, Germany explain the technology and clinical value of D-THI.

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Notable Awards and Honors for Developers

2012 Kanto Regional Commendation for Invention
Encouragement Prize of the Chairman of the Japan Institute of Invention and Innovation

2018 National Commendation for Invention
Award of the Minister of Education, Culture, Sports, Science and Technology

2023 The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology
Awards for Science and Technology

2024 The Medal with Purple Ribbon in the spring of 2024

https://global.medical.canon/News/PressRelease/Detail/150904-834

Clinical images

The use of D-THI improves the distance resolution and the depth sensitivity compared with THI.

Liver

Thyroid

MSK

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